High-Dose
Vitamin C Therapy Proven Effective
“My doctor doesn’t believe in vitamins.”
Since when is medicine based on belief?
(OMNS, January 5, 2010) The medical literature has
virtually ignored 75 years of physician reports and laboratory and clinical
studies on successful high-dose vitamin C therapy.
Effective doses are high doses, often 1,000 times more
than the US Recommended Dietary Allowance (RDA) or Daily Reference Intake
(DRI). It is a cornerstone of medical science that dose affects treatment
outcome. This premise is accepted with pharmaceutical drug therapy, but
not with vitamin therapy. Most unsuccessful vitamin C research has used
inadequate, low doses. Low doses do not get clinical results.
Investigators using vitamin C in high doses have consistently
reported excellent results. High doses were advocated almost immediately
after ascorbic acid was isolated by Albert Szent-Gyorgyi, M.D. (1893-1986).
Notable early medical pioneers of high-dose vitamin C (ascorbate) therapy
are Claus Washington Jungeblut, M.D. (1898-1976); William J. McCormick,
M.D. (1880-1968); and Frederick R. Klenner, M.D. (1907-1984). More recently,
important work has been published by Hugh D. Riordan, M.D. (1932-2005)
and Robert F. Cathcart III, M.D. (1932-2007).
It Was 75 Years Ago Today
Dr. Jungeblut, Professor of Bacteriology at Columbia University, first
published on vitamin C as prevention and treatment for polio, in 1935.
(1) Also in 1935, Jungeblut showed that vitamin C inactivated diphtheria
toxin. (2) By 1937, Jungeblut demonstrated that ascorbate inactivated
tetanus toxin. (3) Between 1943 and 1947, Dr. Klenner, a specialist in
diseases of the chest, cured 41 cases of viral pneumonia with vitamin
C. By 1946, Dr. McCormick showed how vitamin C prevents and also cures
kidney stones; by 1957, how it fights cardiovascular disease. Beginning
in the 1960s, Dr. Cathcart used large doses of vitamin C to treat pneumonia,
hepatitis, and eventually AIDS. For more than three decades, beginning
in 1975, Dr. Riordan and his team have successfully used large doses of
intravenous vitamin C against cancer. The use of doses of tens of thousands
of milligrams of vitamin C per day may be the most unacknowledged successful
research in medicine.
Heard this one before? “If vitamin C was that good,
doctors would tell their patients to take a lot of it.” It is surprising
how many physicians have done precisely that.
What’s that? Your doctor still doesn’t?
Why? Decades of physicians’ reports and controlled
studies support the use of very large doses of vitamin C.
www.orthomolecular.org
References:
(1) Jungeblut CW. Inactivation of poliomyelitis virus by crystalline vitamin
C (ascorbic acid). J Exper Med 1935. 62:317-321.
(2) Jungeblut CW, Zwemer RL. Inactivation of diphtheria toxin in vivo
and in vitro by crystalline vitamin C (ascorbic acid). Proc Soc Exper
Biol Med 1935; 32:1229-34.
(3) Jungeblut CW. Inactivation of tetanus toxin by crystalline vitamin
C (l-ascorbic acid). J Immunol 1937;33:203-214.
For More Information About:
Dr. CW Jungeblut: Claus Washington Jungeblut, M.D.: Polio pioneer; ascorbate
advocate. J Orthomolecular Med, 2006. Vol 21, No 2, p 102-106. http://www.doctoryourself.com/jungeblut.html
In addition to (1) above, Dr. Jungeblut’s other polio
papers include:
Jungeblut CW. Vitamin C therapy and prophylaxis in experimental poliomyelitis.
J Exp Med, 1937. 65: 127-146.
Jungeblut CW. Further observations on vitamin C therapy in experimental
poliomyelitis. J Exper Med, 1937. 66: 459-477.
Jungeblut CW, Feiner RR. Vitamin C content of monkey tissues in experimental
poliomyelitis. J Exper Med, 1937. 66: 479-491.
Jungeblut CW. A further contribution to vitamin C therapy in experimental
poliomyelitis. J Exper Med, 1939. 70:315-332.
Jungeblut’s research published in the Journal of Experimental Medicine
is available for free access at http://www.jem.org/contents-by-date.0.shtml
Dr. FR Klenner: Hidden in plain sight: the pioneering
work of Frederick Robert Klenner, M.D. J Orthomolecular Med, 2007. Vol
22, No 1, p 31-38. http://www.doctoryourself.com/klennerbio.html
http://orthomolecular.org/hof/2005/fklenner.html
Dr. WJ McCormick: The pioneering work of William J.
McCormick, M.D. J Orthomolecular Med, 2003. Vol 18, No 2, p 93-96.
http://www.doctoryourself.com/mccormick.html
http://orthomolecular.org/hof/2004/wmccormick.html
Dr. RF Cathcart:
http://orthomolecular.org/hof/2008/cathcart.html;
http://www.doctoryourself.com/titration.html
http://www.doctoryourself.com/biblio_cathcart.html
Dr. HD Riordan:
http://orthomolecular.org/hof/2005/hriordan.html;
http://orthomolecular.org/resources/omns/v01n09.shtml;
http://www.doctoryourself.com/riordan1.html
http://www.doctoryourself.com/biblio_riordan.html
Nutritional Medicine is Orthomolecular Medicine
Orthomolecular medicine uses safe, effective nutritional therapy to fight
illness. For more information: http://www.orthomolecular.org
The peer-reviewed Orthomolecular Medicine News Service
is a non-profit and non-commercial informational resource.
Editorial Review Board:
Carolyn Dean, M.D., N.D.
Damien Downing, M.D.
Michael Gonzalez, D.Sc., Ph.D.
Steve Hickey, Ph.D.
James A. Jackson, PhD
Bo H. Jonsson, MD, Ph.D
Thomas Levy, M.D., J.D.
Jorge R. Miranda-Massari, Pharm.D.
Erik Paterson, M.D.
Gert E. Shuitemaker, Ph.D.
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